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Juvenile Renal Dysplasia (JRD) is NOT a complicated disease (kidney
disease), it is quite simple to understand and now with the JRD DNA
Test, it is relatively simple to control and possibly eradicate in
breeds that are not saturated with it.
JRD damages kidneys’ to varying degrees
of severity, those with low level damage survive, those with high level
damage die, thankfully deaths are apparently a minority in GSD. (deaths
in the womb and still born may be a more serious concern))
1) Matings of JRD Clear to JRD
Clear - will always produce JRD CLEAR offspring. No need to test
offspring.
2) Matings of JRD Carrier (single)
to JRD Clear - could produce some JRD clear (test & choose from the
clear for breeding)
3) Mating of JRD Carrier (single)
to JRD Carrier (single) could produce some JRD clear, some JRD carriers
and some JRD homozygote’s (double) - test & choose from the clear for
breeding. If no clear choose from the carriers (single) and follow '2'
above process when breeding from the carrier.
4) Mating JRD Homozygote (double)
to JRD Clear - will produce
ALL JRD carriers (single) - no need to test, select one and follow '2'
above process when breeding from the carrier.
5) Mating JRD Homozygote (double)
to a JRD Carrier (single) - could produce JRD Carriers (single) and JRD
Homozygote (double) - test and choose from the JRD Carriers (single) and
then follow '2' above when breeding from it.
6) Mating JRD Homozygote (double)
to JRD Homozygote (double) - will always produce JRD Homozygote (double)
- such a mating should NOT be done.
You cannot currently
treat Hip Dysplasia and many other
diseases this way and control and possibly eradicate them from GSD.
This is the value
of DNA Tests, with some diseases, like JRD; it will be possible to
control and eradicate some of them by DNA Testing and breeding
practices.
Currently, with the apparent low level of
JRD Testing in our GSD breed, stud dogs that are not JRD tested
may be used by kennels that are mating JRD Tested (Clear) females. The
approach I will have when I do this, as when I use a German untested
stud dog, will be to place a breeding restriction on the whole litter
when I register them, which will be removed when they are JRD tested
clear by owners who may wish to breed from them (including those I
retain). Or I may have ALL the puppies JRD tested myself (currently a
bit expensive). A GSD Breed Council scheme which could BULK buy the JRD
tests, and make all the participants JRD results PUBLIC, could make the
JRD Tests much cheaper, possibly up to 40% cheaper.
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